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    A contact lens is used either for therapeutic reasons, corrective purposes or as a cosmetic tool. With the recent advances in the manufa
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    cturing process of contact lenses, anybody can wear them, whether it is a bifocal, daily disposable or astigmatism-correcting lens.

    For
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    millions of people, contact lenses have proven to be a healthy vision option. However, it should be decided only after checking with an
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    eye care professional. If the steps prescribed to removing, inserting and caring for them are rigidly followed the contact lens can be u
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    sed without any trouble. To check the effectiveness or lack of it from the lens, check periodically with an eye care professional.

    If a
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    vision problem is identified and needs a vision correction, one of the viable options is wearing a contact lens. Right from infants who
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    have vision problems at birth, young children, teenagers and all adults can wear contact lenses.

    According to doctors, contact lenses a
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    e the best option for vision correction for athletes. Contact lenses can improve the vision skills such as perception of depth, awarenes
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    s of the peripheral area, co-ordination of eye-foot/eye-hand. Since the contact lens stays in place under dynamic conditions, they offer
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    a total advantage to the athletes. They also free them from the risk of glasses-related injuries.

    According to many eye specialists, co
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    ntact lenses, which are made of a firm plastic lens, may slow or control the progression of myopia or near sightedness. In contrast, con
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    ventional spectacles or soft contact lenses do not offer such advantages.

    In 1971, when contact lenses were introduced it was an advanc
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    d technology and offered comfort not provided by the old-style spectacles. With the latest technology, it is now possible to get better
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    corneal health, sharper vision and a longer life for the lens.

    Contact lenses need cleaning and disinfecting every day. Due to the slic
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    surface offering no scope for building up of deposits, there is no need for frequent enzyming, which is a type of extra-strength cleane
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    r, used weekly, for the removal of stubborn deposits from contact lenses.

    Daily disposal lenses are worn everyday and discarded without
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    any need for maintenance. Weekly disposal contact lens should be cleaned during the night, soaked in a solution containing disinfectants
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    , until they are removed for usage again.

    Color of the eyes also can be changed by using soft contact lenses even if vision correction
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    s not needed. However they are also a prescribed medical device and should be used under the guidance of an eyecare professional. These
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    types of contact lenses are used mostly by theatre and film personalities to get a closer resemblance to the character portrayed by them


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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