Just Articles - Health and Fitness

Dangers of taking Prednisone is really not a subject your doctor discusses with you. I know. I was on prednisone a few times and won't take it ever again. I had taken t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

he medicine by the instructions on the package, the only thing the doctor told to me was take this medicine. Well I sure am glad I read the instructions, which said you

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ake the medicine the way they tell you and in the end you wean yourself off it. Otherwise you can develop problems. And problems is just what I ended up with. I had gon

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e to my family doctor with my elbow swelled up and retaining fluid. Well he didn't know what it was, but put me on prednisone and set up an appointment with a bone speci

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

list. I went to the specialist and found out I had bursitis. He told me to stop taking the prednisone and to take the anabolic that he prescribed. Let me tell you, that

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

is when the problems started. He didn't tell me to wean myself off the prednisone, just to quit taking it. Within three days I ended up with frozen shoulders. That is

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

very painful. I couldn't lift my arms up past my waist. My husband had to comb my hair for me and help me get dressed. I ended up getting acupuncture to loosen up the

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

muscles. They were so stiff and painful, it took quite a few treatments to finally get to where I could use my arms again. Frozen shoulders could last 18 months or longe

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

.

Then I got shots of cortisone in my back for my two herniated disk. The shots worked great but only for a month each time I got one. So much for those. Still not rea

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

lizing that it was a form of steroid.

I guess I still didn't learn a lesson. I ended up with a sinus infection and the doctor put me on prednisone again. This doctor lo

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ed to give prescriptions for that stuff. Well I took it and ended up with thin skin. Now all I have to do is bump my arms or even scratch and the blood comes to the sur

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

face. I end up with red marks or bruises for atleast a week. If I bump my arms to hard the skin actually breaks open.

Well the latest thing is my eyes. I had gone in f

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

r an eye exam. The doctor was a new one I had gone to see and didn't know anything about me and I didn't tell him about my other eye exams until he started questioning me

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

after my exam. He made a remark that my eyes have really changed since my last prescription. Well they take your old glasses and check to see what prescription they ar

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

. My glasses are about 10 months old. I am on my third pair of glasses in a little over two years.

In talking to him, he said there is two things that could make my ey

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

es change like that. Diabetes or cataract. I know I don't have diabetes and the other doctor a couple years ago told me that I have the beginning of a cataract. In talki

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

g to the doctor, he said I am too young to have them. People develop them in their 60's. In talking, he started asking about steroids. Well, it turns out that in the

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

last two and a half years I have had the prednisone and the cordnisone quite a few times.....to many times and it affected my eyes.

The problem with medicines, the docto

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

s want to prescribe them to you but won't tell you the side affects. I usually read the pamphlet they give you with your medicines, and didn't take the dangers of them m

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

edicine to heart and now the medical problems are starting. So if you take medicine please pay attention to the dangers and side affects. And be careful taking steroids

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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