Just Articles - Health and Fitness

The famous Greek philosopher Aristotle once said "You will never do anything in this world without courage. It is the greatest quality of the mind next to honor."

Does it take courage to lose weight? You bet it does! The

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

question then becomes.....do we have the courage to lose weight?

Let's take a look at some of the weight-loss pitfalls we may need courage to overcome. Although all of these won't apply to everyone, we need to be aware of

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

these traps.

* SIBLING RIVALRY - Do you have a sister that you're always competing with? Although we love our siblings, we need to realize that our weight loss success may not always get the warmest response! If we finall

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

y start exercising and drop that extra 40 lbs., but our sister doesn't, how will that impact the sibling relationship? All too often our sister will get jealous and react negatively to our success. A snide comment here, a

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

old shoulder there, and soon we may find ourselves regretting our own success.

* GUILT - Yes, we may even feel guilty about our weight loss success! What if we lose that extra weight, but our best friend doesn't? Similar

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

o 'survivor syndrome', we might even call this phenomenon 'success syndrome'. Consider the woman who, with her mother, has been battling her weight all her life. This has been a journey of 15-25 years!! Suddenly the daught

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

er is thin, and the mother is still obese.....these types of scenarios can create feelings of guilt in the successful person.

* ATTENTION - Once we start exercising regularly, we will start to lose fat and tone muscle. It

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

s likely that, as we become successful in our weight loss efforts, we will start to attract attention from the opposite sex. As fun as that may sound, it may be uncomfortable for some of us.

* SPOUSE - "In a marital or ro

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

mantic relationship there may be an equilibrium that is established over time. Take for example a marriage where a husband smokes or drinks and does not get promoted and his wife is overweight. If she then upsets the equil

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

brium by losing weight, there is implicit pressure on him to make progress in his own areas of struggle.

Another reason that someone may not want their partner to lose weight: Let's say one person is angry and has a diffi

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ult time talking about their feelings, so they badger the other person for having a piece of apple pie. If their partner loses weight, then they no longer have that means to control or express hostility.

Or someone may na

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

g their partner, saying 'You don't look as good as you used to,' but then when their partner begins to lose weight they may resist, not feeling 'good enough' for them any more. One woman told me that her husband was actual

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

y feeding her off his plate. He felt threatened when she lost weight and did his best to undo her weight loss." (Source: Dr. Edward Abramson, a clinical psychologist who specializes in body image. He is the author of Body

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

Intelligence: Lose Weight, Keep it off and Feel Great About your Body Without Dieting, due out in September, 2005 from McGraw-Hill.)

* COURAGE! - It's easy to see that some of us may need courage to cope with our weight l

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ss once we've achieved it. But we CAN find the courage to handle these issues! Some tips for courageous weight loss:
- Invite the jealous sister to exercise with us. If the offer is refused, then remember that we DID

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ake the offer!
- Remember that we can only be responsible for our OWN failure and success.....if a friend or family member fails to lose their excess weight it's not our fault! We are only in charge of us!
- Invi

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

te our spouse to help us shop for healthier foods and cook healthier meals.

Be courageous! WE CAN DO IT!

* Copyright 2005 Pick Up The Pace. Permission is not required for the distribution of Pick Up The Pace articles as

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ong as they are used in their entirety, are properly credited to Pick Up The Pace, and are accompanied by our website link: www.letspickupthepace.com.

* The information in this article and on this site is for general refe

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

rence purposes only and not intended to address specific medical conditions. This information is not a substitute for professional medical advice or a medical exam. Prior to participating in any exercise program or activit

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

, you should seek the advice of your physician or other qualified health professional. No information in this article or on www.letspickupthepace.com should be used to diagnose, treat, cure or prevent any medical condition

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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